Single electronic submissions of the IRAS Form for studies led from Northern Ireland, Scotland and Wales On 28 June 2018 an update to IRAS, the Integrated Research Application System, will introduce a single, e-submission of IRAS Forms and associated documents. This change applies to studies taking place in NHS organisations in Scotland and Wales and Health and Social Care (HSC) organisations in Northern Ireland where the lead NHS/HSC R&D office is in Northern Ireland, Scotland or Wales. Single IRAS Form and document e‑submission is already available for NHS/HSC studies where the lead NHS R&D office is in England. There is no change to how participating organisations are set up. IRAS Help provides advice on how to submit site specific/ local information to sites. Read more at: Four Nations Compatibility webpage.